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Mesothelioma and Non Asbestos Exposure Mesothelioma typically develops in the lung's lining (pleura) and abdomen (peritoneum). The rare cancer may also develop in the linings around the heart or the testes (pericardium). Asbestos is the most significant mesothelioma-related risk factor. Some people with mesothelioma do not have any prior history of exposure to asbestos. Exposure to Asbestos Asbestos, which is a mineral of natural origin, was previously used for industrial and construction products throughout the world. People who worked in asbestos-related industries handled the mineral on a daily basis, putting them at risk of exposure. Asbestos fibers can get into the lungs, causing progressive lung diseases. This is called asbestosis. Over time, these fibers that have been trapped in the lungs may cause mesothelioma. Asbestos fibers can be breathed in, ingested or even absorbed through the skin. The chance of developing mesothelioma and other asbestos-related diseases increases with exposure. The majority of mesothelioma cases stem from occupational exposure. Asbestos was employed in a variety of trades, including construction insulation and electrical work, as well as automobile maintenance and pipefitting. These trades are typically heavily populated by males and as a consequence mesothelioma cases involving males comprise 75-80% of all reported cases. The elimination of asbestos in the United States, and other first-world countries has reduced the risk of contamination. This has led to an increase in cases with non-occupational exposure increasing. Non-occupational mesothelioma may occur when asbestos is released from the workplace environment or found in the school or home environment. It can also result from exposure through secondhand sources for example, when a family member is exposed to the clothing of an asbestos-working worker. The people who suffer from this type of exposure might experience symptoms like breathing problems or chest pain that is often mistaken as heart or lung conditions. Certain studies have linked mesothelioma to non-occupational exposure, but the results differ. Many of these studies were conducted with a small sample size, and within-study heterogeneity has been high. It is necessary to conduct further studies to confirm the connection between asbestos exposure in non-occupational settings and mesothelioma. Anyone who has been exposed to asbestos in non-occupational settings should consult their doctor regarding their asbestos-related background. If they are concerned, they should ask for a mesothelioma test and a referral to an expert. Specialists in mesothelioma can offer the most effective treatment and treatment to improve a patient's chances of survival. They will review medical records, and carry out imaging tests to identify the disease. They will also provide advice on how to file mesothelioma suit to get compensation from asbestos trust fund. Secondhand Exposure While exposure to asbestos is the leading cause of mesothelioma not the only way to develop this disease. There is evidence to suggest that people who have never been exposed to asbestos or worked in a workplace with asbestos-related activities can still develop mesothelioma. This is referred to as secondary or non-occupational exposure to asbestos. Asbestos fibres are very small and can adhere to clothing, hair and skin. As a result, workers may bring the harmful fibers home with them on their work clothes and then transfer them to family members. These asbestos fibers could be inhaled or swallowed, which can cause mesothelioma. This mesothelioma type occurs more frequently in women and is usually found in the lung. However, it could also be found in the abdomen and the chest wall. A shortness of breath is the most typical symptom. It is often associated with a range of other symptoms, like fluid in the lungs or swelling in the scrotum. The mesothelioma that develops in the lungs is known as mesothelioma of the pleural region. Peritoneal mesothelioma refers to the name for mesothelioma, which affects the stomach wall or the chest wall. This type of mesothelioma can cause a variety of symptoms, including abdominal pain, difficulty breathing, and constipation. A number of studies have shown that people with no background of occupational exposure to asbestos could get mesothelioma because of secondhand exposure to the harmful fibers. These individuals typically lived with someone who was exposed to asbestos. They might have touched the clothing of the asbestos worker, or had other contact. Veterans are at a higher risk of mesothelioma because asbestos was widely used in military bases as well as vehicles and ships. The Navy is especially at risk because asbestos was used to insulate the hull the ship and to fireproof gun turrets. In addition, sailors frequently brought asbestos home from work on ships that were contaminated with the material. Environmental Exposure Mesothelioma is linked to various substances. However, the disease is most often associated with exposure to asbestos. Asbestos is a mineral that occurs naturally is used in the manufacture of products for a long time. The mineral is resistant to heat and strong which makes it suitable for insulation, brakes and flooring, shingles, and other items. Asbestos is broken down to dust that can be inhaled and swallowed. These fibers may remain in the lungs and stomach for a long time, and trigger mesothelioma-related symptoms. The most frequent mesothelioma symptoms are chest pain as well as abdominal discomfort, and difficulty breathing. Asbestos exposure can cause these symptoms to persist for up to 60 years. It is important to consult your doctor if you notice these symptoms. It is also important to tell your doctor about your previous history of asbestos. This will prevent a faulty diagnosis and ensure that you receive the proper treatment. The most common mesothelioma victims from asbestos exposure are those who have worked directly with asbestos, but it is also possible for loved relatives to be affected. This is referred to as secondary exposure. Family members could take in asbestos fibers from a worker's shoes, clothing or other tools. These particles can also be brought to home by someone who is wearing or having their hair. It is for this reason that mesothelioma sufferers as well as their families must always clean their clothes after working with asbestos. There is a significant body of literature that shows the connection between exposure to asbestos and mesothelioma. However, there is no conclusive evidence yet on the role of other agents. For example, there is some evidence that the zeolites erionite and chlorosotile can cause mesothelioma. Erionite is found in soil and rocks in certain regions of Turkey where pleural mesothelioma rates are high. Research into the relationship between mesothelioma exposure and asbestos exposure is ongoing. Funnel plots have revealed the possibility of publication bias, and there is a high degree of heterogeneity between studies. However, it is still evident that occupational exposure to asbestos is the most important risk factor for mesothelioma. Genetics Mesothelioma is a rare condition caused by malignant mesothelial cells that expand beyond control and invade surrounding tissues. It can be spread throughout the body by passing through the lymphatic system or bloodstream and impacting other organs. Although asbestos is the primary cause of mesothelioma is not the only risk factor. The condition could be caused by other genetic or environmental factors. In some instances mesothelioma is seen in people who had no direct exposure to asbestos. They are known as non-occupational mesothelioma patients. They were usually exposed through the handling of hazardous household items or clothing by someone who was exposed to asbestos in their home. For Fort Smith asbestos attorney , it is possible for someone to be diagnosed with pleural mesothelioma based on the exposure to asbestos fibers in clothing belonging to a loved ones. Studies show that these types of mesothelioma patients tend to have longer periods of latency and are more likely to be diagnosed in wives than in husbands. Scientists are currently studying the possibility that mesothelioma's genetic predisposition could play a part in the development of the disease. Recent studies have shown the mutation in the gene BAP1 increases the risk of mesothelioma among asbestos-exposed people. This finding is significant as it could lead improved screening methods for those who are at a high risk of developing mesothelioma. Researchers have identified a variety of genes that are related to mesothelioma. These genes are often mutated in mesothelioma and suppress tumor growth. These genes include the massive homolog of tumor suppressor 2 (LATS2) and the NF2. A family history of the disease can increase the risk. This is due to the fact that certain genes, including the BAP1 gene, can be passed down from the parents. Veterans have the highest rates of mesothelioma in comparison to other occupational groups because asbestos was extensively used in the military. The people who served in the Navy and on ships were particularly at risk the most due to the high exposure to asbestos in insulation, fireproofing materials and shipbuilding.